Positive response to ‘gift tokens for undetectable viral load’ trial

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A US study
presented at last month’s HIV Research for Prevention conference found generally
positive responses among people with HIV and clinic staff to a trial that used
$70 gift tokens as an incentive for people to attend clinic regularly,
refill their HIV treatment drug prescriptions, and maintain an undetectable viral load.
However, the
study found

Sofosbuvir + GS-5816 for 12 weeks shows high HCV cure rates, but 8 weeks is less effective for some patients

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A 12-week oral combination
of sofosbuvir plus the experimental NS5A inhibitor GS-5816 demonstrated high
sustained virological response rates for people with difficult-to-treat HCV
genotype 3 and other genotypes, according to phase 2 study findings presented at
the American Association for the Study of Liver
Diseases (AASLD) Liver Meeting last week in Boston. Reducing treatment duration

In futuro basterà una sola pillola per eradicare l’infezione

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«Le opzioni terapeutiche di cui disponiamo, incluse le più recenti, nonostante la loro indiscutibile efficacia, lasciano aperti numerosi problemi: sono attive principalmente contro i genotipi 1 e 4 di HCV, e molto meno efficaci per circa un terzo dei pazienti, quelli con genotipo 2 e 3, e non danno risposte soddisfacenti in presenza di cirrosi compensata e scompensata.

People living with HIV have high survival rates after liver transplants due to HCC

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People with HIV – most of whom had hepatitis B
or C co-infection – generally had good outcomes after liver transplantation due
to hepatocellular carcinoma (HCC), with five-year survival rates similar to
those of HIV-negative transplant recipients and better than those of people who
underwent other types of liver cancer treatment, researchers reported this

What are the barriers that could stop HIV treatment becoming HIV prevention?

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One of the key strategies involved in trying to bring an end
to the HIV epidemic is to increase the proportion of HIV-positive people on antiretroviral
therapy (ART), to the point where suppressing their viral load starts to reduce
onward infection.
What is usually called ‘treatment as prevention’ lies behind
the
ambitious new target announced

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