Increased expenditure on social security has benefits for TB control in the EU

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Increased
expenditure on social protection programmes – sickness, disability and
unemployment benefits, old age pensions, housing support – is associated with
improved tuberculosis (TB) control, according to an analysis of data from
European Union (EU) countries published in Lancet
Infectious Diseases.
“Social protection
spending is strongly associated with lower tuberculosis case notification,
incidence, and mortality rates,” comment the

Second European PrEP study is closed early due to high effectiveness

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In
an extraordinary development, a second European scientific trial of
pre-exposure prophylaxis (PrEP) has had its randomised phase closed early due
to high effectiveness, just
two weeks after the UK PROUD trial did exactly the same thing.
The
investigators of the IPERGAY trial, which has six sites in France and one in
Canada, announced today a “Significant

How does a ‘human rights based approach’ work out on the ground? Lessons from South Africa

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While international rhetoric on HIV and AIDS frequently
invokes human rights, putting these ideas into practice in specific settings
remains challenging, according to a process evaluation of an intervention in
rural South Africa published in the October issue of Culture, Health and Sexuality. Although female health volunteers
understood gender inequalities to be a key

NNRTIs and protease inhibitors both good for first ART, channelling affects choices

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Non-nucleoside
reverse transcriptase inhibitors (NNRTIs) and boosted protease
inhibitors work equally well for people starting HIV treatment for the first
time, with similar viral suppression, CD4 cell gains, and disease
progression, according to a large meta-analysis presented
at IDWeek 2014 earlier this month in Philadelphia. A related study
shed light on factors affecting choice of
initial antiretroviral regimen.

Infants in southern Africa start antiretroviral therapy late with advanced disease

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Three
quarters of infants starting antiretroviral therapy (ART) across eleven clinics in southern Africa had
severe HIV disease and 87.2% met the 2006 World Health Organization (WHO)
definition of severe immunosuppression, according to a study presented at the
2014 Southern African HIV Clinicians Society conference in Cape Town, South Africa, last
month.
There
was a modest improvement

Infants in southern Africa start antiretroviral therapy late with advanced disease

postato in: Senza categoria | 0

Three
quarters of infants starting antiretroviral therapy (ART) across eleven clinics in southern Africa had
severe HIV disease and 87.2% met the 2006 World Health Organization (WHO)
definition of severe immunosuppression, according to a study presented at the
2014 Southern African HIV Clinicians Society conference in Cape Town, South Africa, last
month.
There
was a modest improvement

Sofosbuvir/ledipasvir safe and effective for genotype 1 HCV

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A single-tablet
regimen containing the hepatitis C virus (HCV) nucleotide polymerase
inhibitor sofosbuvir and
the NS5A inhibitor ledipasvir - the combination in Gilead Science’s
recently approved Harvoni pill - was well-tolerated and cured 97% of
patients with HCV genotype 1 in the Phase 3 ION trials, researchers
reported at the IDWeek 2014 meeting earlier this month in
Philadelphia.
The
advent of direct-acting antiviral agents has revolutionized treatment for
chronic hepatitis C, especially with the long-awaited

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