News HIV/AIDS

Il virus Hiv ancora ‘bambino’, immaturo e incapace di infettare, è stato fotografato per la prima volta in alta definizione dai ricercatori del Laboratorio europeo di biologia molecolare (Embl) in collaborazione con l’università tedesca di Heidelberg. Le immagini, pubblicate su Nature, dimostrano che i ‘mattoni’ che compongono il virus sono disposti in una maniera del tutto inattesa: conoscere la loro esatta posizione permetterà di sviluppare nuovi farmaci mirati per bloccare il processo di maturazione.

Around one-third of people
living with HIV in Eastern Europe who were diagnosed with TB had multi-drug
resistant TB, according to the findings of a global study of TB/HIV management
in high- and middle-income countries. The findings of the study, condu…

Many young gay men consider ‘safer sex’ to be about more
than condom use, according to a qualitative study conducted in Scotland. Encouragingly,
many consider regular HIV testing to be a component of safer sex. More
problematically, condomless sex with a regular partner was described as being
relatively safe, even when there was little

A phase one dose-finding and safety study in humans of TMC278
LA, a long-acting, injectable formation of the antiretroviral (ARV) drug
rilpivirine, found that a single 1200-mg dose could produce sustained drug levels
in rectal tissues that could offer …

The
risk of acquiring herpes simplex virus type 2 (HSV-2) was reduced by 46% (aIRR:0.54,
95%CI:0.30-0.97, p=0.038) among women who regularly used the vaginal gel
containing tenofovir, according to a secondary analysis of the Vaginal and Oral
Interventi…

Researchers
have determined the dose of an injectable formulation of the integrase inhibitor cabotegravir
(formerly GSK744) that will be taken into efficacy trials to see if it can be
used for pre-exposure prophylaxis (PrEP). Studies
in animals were pr…

Increased
expenditure on social protection programmes – sickness, disability and
unemployment benefits, old age pensions, housing support – is associated with
improved tuberculosis (TB) control, according to an analysis of data from
European Union (EU) countries published in Lancet
Infectious Diseases.
“Social protection
spending is strongly associated with lower tuberculosis case notification,
incidence, and mortality rates,” comment the

“There’s
only one Berlin patient still. But by this time next year he will at least be
joined by 40-50 Portland monkeys.”  This
was vaccine researcher Louis Picker, summarising in quotable form why the
outlook for the development of an effective HIV vaccine is brighter than it has
been for years, in a Satellite session

In
an extraordinary development, a second European scientific trial of
pre-exposure prophylaxis (PrEP) has had its randomised phase closed early due
to high effectiveness, just
two weeks after the UK PROUD trial did exactly the same thing.
The
investigators of the IPERGAY trial, which has six sites in France and one in
Canada, announced today a “Significant

While international rhetoric on HIV and AIDS frequently
invokes human rights, putting these ideas into practice in specific settings
remains challenging, according to a process evaluation of an intervention in
rural South Africa published in the Octobe…